Lengyel/Kenny Lab Publications


For further overviews about ovarian cancer and specific areas of expertise in the laboratory, please see our review article on ovarian cancer biology (American Journal of Pathology), or reviews on experimental models and 3D organotypic cultures, interaction between adipose tissue and cancer, and long-term survival of ovarian cancer patients. Please review our recent publications: 

  • Weigert M, Cui XL, West-Szymanski D, Yu X, Bilecz AJ, Zhang Z, Dhir R, Kehoe M, Zhang W, He C, Lengyel E. 5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer. Gynecol Oncol. 2024 Jan 22;182:82-90. doi: 10.1016/j.ygyno.2024.01.001. Epub ahead of print. PMID: 38262243.
  • Weigert M, Li Y, Zhu L, Eckart H, Bajwa P, Krishnan R, Ackroyd S, Lastra RR, Bilecz A, Basu A, Lengyel E, Chen M. A Cellular atlas of the human fallopian tube reveals the metamorphosis of secretory epithelial cells during the menstrual cycle and menopause. medRxiv [Preprint]. 2023 Nov 23:2023.11.22.23298470. doi: 10.1101/2023.11.22.23298470. PMID: 38045369; PMCID: PMC10690352.
  • Schweizer L, Krishnan R, Shimizu A, Metousis A, Kenny H, Mendoza R, Nordmann TM, Rauch S, Kelliher L, Heide J, Rosenberger FA, Bilecz A, Borrego SN, Strauss MT, Thielert M, Rodriguez E, Müller-Reif JB, Chen M, Yamada SD, Mund A, Lastra RR, Mann M, Lengyel E. Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression. medRxiv [Preprint]. 2023 Nov 13:2023.11.13.23298409. doi: 10.1101/2023.11.13.23298409. PMID: 38014221; PMCID: PMC10680885.
  • Mukherjee A, Bezwada D, Greco F, Zandbergen M, Shen T, Chiang CY, Tasdemir M, Fahrmann J, Grapov D, La Frano MR, Vu HS, Faubert B, Newman JW, McDonnell LA, Nezi L, Fiehn O, DeBerardinis RJ, Lengyel E. Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis. Nat Metab. 2023 Sep;5(9):1563-1577. doi: 10.1038/s42255-023-00879-8. Epub 2023 Aug 31. PMID: 37653041.
  • Yoeli-Bik R, Longman RE, Wroblewski K, Weigert M, Abramowicz JS, Lengyel E. Diagnostic Performance of Ultrasonography-Based Risk Models in Differentiating Between Benign and Malignant Ovarian Tumors in a US Cohort. JAMA Netw Open. 2023 Jul 3;6(7):e2323289. doi: 10.1001/jamanetworkopen.2023.23289. PMID: 37440228; PMCID: PMC10346125.
  • Bajwa P, Kordylewicz K, Bilecz A, Lastra RR, Wroblewski K, Rinkevich Y, Lengyel E, Kenny HA. Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis. JCI Insight. 2023 Mar 22;8(6):e163019. doi: 10.1172/jci.insight.163019. PMID: 36795484; PMCID: PMC10070116.
  • Lengyel E, Li Y, Weigert M, Zhu L, Eckart H, Javellana M, Ackroyd S, Xiao J, Olalekan S, Glass D, Iyer S, Krishnan R, Bilecz AJ, Lastra R, Chen M, Basu A. A molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencing. Cell Rep. 2022 Dec 20;41(12):111838. doi: 10.1016/j.celrep.2022.111838. PMID: 36543131.
  • Javellana M, Eckert MA, Heide J, Zawieracz K, Weigert M, Ashley S, Stock E, Chapel D, Huang L, Yamada SD, Ahmed AA, Lastra RR, Chen M, Lengyel E. Neoadjuvant Chemotherapy Induces Genomic and Transcriptomic Changes in Ovarian Cancer. Cancer Res. 2022 Jan 1;82(1):169-176. doi: 10.1158/0008-5472.CAN-21-1467. Epub 2021 Nov 4. PMID: 34737212; PMCID: PMC8936832.
  • See the NCBI listing of Dr. Lengyel's publications
  • See the citation index for Dr. Lengyel in Google Scholar
  • See the NCBI listing of Dr. Kenny's publications
  • See the citation index for Dr. Kenny in Google Scholar