Lengyel Lab Publications

 

For further overviews about ovarian cancer and specific areas of expertise in the laboratory, please see our review article on ovarian cancer biology (American Journal of Pathology), or reviews on experimental models and 3D cultures in ovarian cancer, and the interaction between adipose tissue and cancer. "Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer," Nature Reviews Cancer, may also be of interest as it contains proposals by an international group of researchers for improving ovarian cancer survival. 

  • Curtis M, Kenny HA, Ashcroft B, Mukherjee A, Johnson A, Zhang Y, Helou Y, Batlle R, Liu X, Gutierrez N, Gao X, Yamada SD, Lastra R, Montag A, Ahsan N, Locasale JW, Salomon AR, Nebreda AR, Lengyel E. Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis. Cell Metab. 2019 Jan 8;29(1):141-155.e9. doi: 10.1016/j.cmet.2018.08.007. Epub 2018 Aug 30. PMID: 30174305; PMCID: PMC6326875.
  • Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaženović I, Lastra RR, Curtis M, Yamada SD, Perets R, McGregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel E. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019 May;569(7758):723-728. doi: 10.1038/s41586-019-1173-8. PMID: 31043742; PMCID: PMC6690743.
  • Dauer P, Lengyel E. New Roles for Glycogen in Tumor Progression. Trends Cancer. 2019 Jul;5(7):396-399. doi: 10.1016/j.trecan.2019.05.003. PMID: 31311654.
  • Mukherjee A, Chiang CY, Daifotis HA, Nieman KM, Fahrmann JF, Lastra RR, Romero IL, Fiehn O, Lengyel E. Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance. Cancer Res. 2020 Apr 15;80(8):1748-1761. doi: 10.1158/0008-5472.CAN-19-1999. PMID: 32054768.
  • Eckert MA, Orozco C, Xiao J, Javellana M, Lengyel E. The Effects of Chemotherapeutics on the Ovarian Cancer Microenvironment. Cancers (Basel). 2021 Jun 23;13(13):3136. doi: 10.3390/cancers13133136. PMID: 34201616; PMCID: PMC8268261.
  • Javellana M, Eckert MA, Heide J, Zawieracz K, Weigert M, Ashley S, Stock E, Chapel D, Huang L, Yamada SD, Ahmed AA, Lastra RR, Chen M, Lengyel E. Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer. Cancer Res. 2021 Nov 4:canres.1467.2021. doi: 10.1158/0008-5472.CAN-21-1467.PMID: 34737212.
  • See the NCBI listing of Dr. Lengyel's publications
  • See the citation index for Dr. Lengyel in Google Scholar