People

Richard Koya, MD PhD

Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest. 2023 Dec 15; 133(24).
PMID: 38099495

Implementation of a gene therapy education initiative by the ASGCT and Muhimbili University of Health and Allied Sciences.
Implementation of a gene therapy education initiative by the ASGCT and Muhimbili University of Health and Allied Sciences. Mol Ther. 2023 09 06; 31(9):2561-2565.
PMID: 37595584

Correction to: Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.
Correction to: Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction. Cancer Immunol Immunother. 2022 Dec; 71(12):2899.
PMID: 35666273

Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses. Cancer Cell. 2022 10 10; 40(10):1145-1160.e9.
PMID: 36150390

pH Sensitive Erythrocyte-Derived Membrane for Acute Systemic Retention and Increased Infectivity of Coated Oncolytic Vaccinia Virus.
pH Sensitive Erythrocyte-Derived Membrane for Acute Systemic Retention and Increased Infectivity of Coated Oncolytic Vaccinia Virus. Pharmaceutics. 2022 Aug 28; 14(9).
PMID: 36145558

Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.
Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction. Cancer Immunol Immunother. 2022 Dec; 71(12):2881-2898.
PMID: 35460379

Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.
Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses. Sci Transl Med. 2022 03 16; 14(636):eabg8402.
PMID: 35294258

Engineering tumor stromal mechanics for improved T cell therapy.
Engineering tumor stromal mechanics for improved T cell therapy. Biochim Biophys Acta Gen Subj. 2022 04; 1866(4):130095.
PMID: 35077823

CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer.
CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer. J Immunother Cancer. 2021 10; 9(10).
PMID: 34607898

Engineered microenvironment for the study of myofibroblast mechanobiology.
Engineered microenvironment for the study of myofibroblast mechanobiology. Wound Repair Regen. 2021 07; 29(4):588-596.
PMID: 34118169

View All Publications